Therapeutic dimethyl sulfoxide composition and methods of use

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Monoclonal antibody or fragment thereof

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424322, 424337, A61K 3110, A61K 3117, A61K 3314

Patent

active

042961041

ABSTRACT:
The use of urea and/or ethanol with pharmaceutical compositions containing DMSO is disclosed. The result is a reduction in the undesirable side-effects normally associated with the application of DMSO compositions, enhancement of the desired physiological effects produced by DMSO compositions, and other benefits. Specific compositions contain DMSO with urea and/or alcohol and may also contain NaCl, KCl and/or acetamide.
The use of DMSO to reduce the mortality rate of fish treated by hyperosmotic delivery is also disclosed.

REFERENCES:
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patent: 3549770 (1970-12-01), Herschler
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patent: 3551554 (1970-12-01), Herschler
patent: 3558434 (1971-01-01), Herschler
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patent: 3740420 (1973-01-01), Herschler
patent: 3743727 (1973-07-01), Herschler
patent: 4112946 (1978-09-01), Herschler
patent: 4177267 (1979-12-01), Herschler
Mallach, 141, Annals New York Academy of Sciences, pp. 457-462.

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