Drug – bio-affecting and body treating compositions – Identification or warning feature – Taste or smell or chemical irritation to the eye – nose – or...
Patent
1977-12-27
1979-07-03
Rose, Shep K.
Drug, bio-affecting and body treating compositions
Identification or warning feature
Taste or smell or chemical irritation to the eye, nose, or...
128260, 424 19, 424 21, 424 35, A61M 3100, A61K 924, A61K 944
Patent
active
041600207
ABSTRACT:
An osmotic device is disclosed for delivering an active agent. The device comprises a wall surrounding a compartment with a passageway through the wall for releasing the agent. The wall comprises a material permeable to an external fluid and substantially impermeable to agent and at least one additional material independently selected from materials that impart stability to the wall, enhance the permeability of the wall to fluids, or aid in forming the wall. The compartment contains an agent that exhibits an osmotic pressure gradient across the wall against an external fluid, or the agent is mixed with an osmotically effective compound that exhibits an osmotic pressure gradient against the fluid. Agent is released from the device by fluid being imbided through the wall into the compartment at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall, thereby producing a solution containing agent that is released through the passageway at a controlled rate over time.
REFERENCES:
patent: 4077407 (1978-03-01), Theeuwes et al.
Ayer Atul D.
Theeuwes Felix
ALZA Corporation
Ciotti Thomas E.
Mandell Edward L.
Rose Shep K.
Sabatine Paul L.
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