Therapeutic/cosmetic compositions comprising bradykinin antagoni

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Cosmetic – antiperspirant – dentifrice

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424 43, 424 49, 424 701, 424489, 514844, 514846, 514936, 514944, A61K 748

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058493123

ABSTRACT:
Topically applicable pharmaceutical/dermatological/cosmetic compositions well suited for the therapeutic treatment or care of sensitive human skin, hair, mucous membranes, nails and/or the scalp, in particular for reducing or avoiding the skin-irritant side effects of a variety of bioactive agents, for example the .alpha.-hydroxy and .beta.-hydroxy acids, comprise a therapeutically/cosmetically effective amount of at least one bradykinin antagonist.

REFERENCES:
Neuroscience, vol. 48, No. 4, 1992, pp. 963-968.
British Journal of Pharmacology, vol. 110, No. 2, Oct. 1993, pp. 772-776.
British Journal of Pharmacology, vol. 104, No. 3, Nov. 1991, pp. 738-742.
British Journal of Pharmacology, vol. 109, No. 1, 1993, pp. 259-264.
British Journal of Dermatology, vol. 124, No. 4, 1991, pp. 324-328.
Contact Dermatitis, vol. 19, No. 5, 1988, pp. 351-354.

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