Therapeutic compounds for treating dyslipidemic conditions

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S230800, C514S241000, C514S254020, C514S255050, C514S256000, C514S269000, C514S274000, C514S338000, C514S369000, C514S379000, C540S524000, C544S137000, C544S220000, C544S310000, C544S331000, C544S368000, C544S405000, C546S272100, C548S183000, C548S241000

Reexamination Certificate

active

07125865

ABSTRACT:
The present invention relates to novel LXR ligands of Formula I and the pharmaceutically acceptable salts, esters and tautomers thereof, which are useful in the treatment of dyslipidemic conditions, particularly depressed levels of HDL cholesterol.

REFERENCES:
patent: 6008237 (1999-12-01), Sahoo et al.
patent: 6908934 (2005-06-01), Adams et al.
patent: 2002/0173663 (2002-11-01), Liu et al.
patent: 2003/0086923 (2003-05-01), Sparrow et al.
patent: 2003/0125357 (2003-07-01), Adams et al.
patent: WO 01/41704 (2001-06-01), None
patent: WO 03/045382 (2003-06-01), None
patent: WO 03/053352 (2003-07-01), None
Menke, et al., Endocrinology, “A Novel Liver X Receptor Agonist Establishes Species Differences in the Regulation of Cholesterol 7alpha-Hydroxylase (CYP7a)”, 143(7) pp. 2548-2558, Jul. 2002.

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