Therapeutic compounds derived from the neem tree

Details Therapeutic compounds derived from the neem tree Therapeutic compounds derived from the neem tree

1992-09-11

1994-12-06

Rollins, John W.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Conjugate or complex

514934, 514896, A61K 3578

Patent

active

053708733

ABSTRACT:
The present invention relates to purified extracts from Neem leaves. The extracts inhibit the adhesion of infectious cells and cancer cells to endothelial cells. The extracts also inhibit viruses, and malaria parasites in both the asexual and sexual forms. The invention also relates to a method of extraction, and pharmaceutical preparations containing the purified extracts.

REFERENCES:
patent: 4515785 (1985-05-01), Simiza et al.
patent: 4536496 (1985-08-01), Shimiza et al.
patent: 4537774 (1985-08-01), Shimiza et al.
patent: 5196197 (1993-03-01), Talwar et al.
Pettit et al., Journal of Natural Products 46, 379 (1983).
Fujiwara et al., Carbohydrate Research 141, 168 (1985).
E. Sandstrom et al. Drug 34: 372-398, 1987.
Chung Chu et al. J Med Chem 32: 612-617, 1989.

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