Therapeutic compounds

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

C544S276000, C544S277000

Reexamination Certificate

active

07906518

ABSTRACT:
The invention relates to a method of improving oral drug absorption of adenosine analogues by the use of 2′,3′-methylidene acetal adenosine pro-drugs and to the use of these pro-drugs as medicaments. The invention further relates to compounds that are pro-drugs of adenosine receptor agonists, and to their use as therapeutic compounds, in particular as analgesic or anti-inflammatory compounds, or as disease modifying antirheumatic drugs (DMARDs), and to methods of preventing, treating or ameliorating pain or inflammation using these compounds.

REFERENCES:
patent: 6117878 (2000-09-01), Linden
patent: 6894021 (2005-05-01), Belardinelli et al.
patent: 7553823 (2009-06-01), Zablocki et al.
patent: 2002/0147174 (2002-10-01), Jones et al.
patent: 2003/0040502 (2003-02-01), Salzman et al.
patent: 2004/0180948 (2004-09-01), Linden et al.
patent: 2004/0266722 (2004-12-01), Devos et al.
patent: 2005/0059683 (2005-03-01), Zablocki et al.
patent: 2005/0159388 (2005-07-01), Plourde et al.
patent: 2005/0261236 (2005-11-01), Okusa et al.
patent: 2007/0093446 (2007-04-01), Douglass et al.
patent: 2007/0123544 (2007-05-01), Plourde et al.
patent: 2007/0208040 (2007-09-01), Elzein et al.
patent: 2007/0219221 (2007-09-01), Zeng et al.
patent: 2007/0232626 (2007-10-01), Jacobson et al.
patent: 2007/0274910 (2007-11-01), Wilson et al.
patent: 2007/0299089 (2007-12-01), Belardinelli et al.
patent: 2008/0027022 (2008-01-01), Linden et al.
patent: 2008/0176858 (2008-07-01), Beauglehole et al.
patent: 2008/0214581 (2008-09-01), Allen et al.
patent: 2008/0242673 (2008-10-01), Moorman
patent: 2008/0262001 (2008-10-01), Kranenburg et al.
patent: 2008/0312160 (2008-12-01), Guerrant et al.
patent: 2009/0012035 (2009-01-01), Jacobson et al.
patent: 2009/0054476 (2009-02-01), Goblyos et al.
patent: 2009/0081764 (2009-03-01), Pausch et al.
patent: 2009/0099212 (2009-04-01), Zablocki et al.
patent: 2009/0123510 (2009-05-01), Cronstein et al.
patent: 2009/0156544 (2009-06-01), Elzein et al.
patent: 2009/0170805 (2009-07-01), Tan et al.
patent: 2009/0181920 (2009-07-01), Watkins et al.
patent: 2009/0203689 (2009-08-01), Dhalla et al.
patent: 2009/0247745 (2009-10-01), Aranyi et al.
patent: 2009/0325967 (2009-12-01), Fairhurst et al.
patent: 0997473 (2000-05-01), None
patent: 1491201 (2004-12-01), None
patent: WO-2004052377 (2004-06-01), None
patent: WO-2004078183 (2004-09-01), None
patent: WO-2004078184 (2004-09-01), None
patent: WO-2005084653 (2005-09-01), None
Keeling, Suzanne E. et al., “The Discovery and Synthesis of Highly Potent, A2a Receptor Agonists,” Bioorganic & Medicinal Chemistry Letters 2000, vol. 10, p. 403-406.
Doytchinova, I. et al., “Adenosine A2A receptor agonists: CoMFA-based selection of the most predictive conformation,” SAR and QSAR in Environmental Research 2002, vol. 13, No. 2, p. 227-235.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

Therapeutic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic compounds will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-2682954

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.