Therapeutic compositions with controlled release of medicaments

Details Therapeutic compositions with controlled release of medicaments Therapeutic compositions with controlled release of medicaments

1990-12-03

1994-01-04

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424469, 424486, 424487, 424489, 424497, 514 58, A61K 916

Patent

active

052758249

ABSTRACT:
The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using either swelling with solutions of the medicament or high-energy co-grinding methods. The medicament-loaded particles are coated with a polymers film able to control medicament release, to obtain a prolonged release of the medicament (even exceeding 24 hours) while maintaining high bioavailability.

REFERENCES:
patent: 4973469 (1990-11-01), Mulligan et al.

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