Therapeutic compositions comprising bactericidal/permeability-in

Details Therapeutic compositions comprising bactericidal/permeability-in Therapeutic compositions comprising bactericidal/permeability-in

1996-01-12

1999-06-15

Lau, Kawai

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530350, A61K 3817, C07K 1447

Patent

active

059122285

ABSTRACT:
Improved therapeutic compositions having enhanced anti-microbial activity comprising a bactericidal/permeability-increasing (BPI) protein product and an bactericidal-activity enhancing polyoxyethylene block copolymer surfactant (poloxamer) surfactant or a bacterial and fungal growth-inhibiting enhancing poloxamer surfactant, optionally with EDTA, and methods for treating bacterial infection by administering such compositions, alone or concurrently with antibiotics.

REFERENCES:
patent: 5447913 (1995-09-01), Ammons et al.
patent: 5488034 (1996-01-01), McGregor et al.
patent: 5578572 (1996-11-01), Horwitz et al.

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