Therapeutic compositions comprising alpha-hydroxy analogs of ess

Details Therapeutic compositions comprising alpha-hydroxy analogs of ess Therapeutic compositions comprising alpha-hydroxy analogs of ess

1976-03-23

1978-07-11

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Fungus, except allergen, or component thereof or substance...

424317, 424319, A61K 3119, A61K 3140, A61K 31195

Patent

active

041001605

ABSTRACT:
Compositions containing the hydroxy analogs of certain essential amino acids are formulated for therapeutic use, particularly in the treatment of renal disorders, hepatic failure and conditions of protein wasting in human subjects. In preferred embodiments, keto analogs of certain essential amino acids are used in combination with hydroxy analogs of other essential amino acids.

REFERENCES:
patent: 2457820 (1949-01-01), Howe et al.
patent: 3764703 (1973-10-01), Bergstrom
Chemical Abstracts 81:54452q (1974).
Chemical Abstracts 82:144958j (1975).
Richards et al., Lancet, pp. 128-134, (Jul. 17, 1971).
Richards et al., Lancet pp. 845-849, (Oct. 21, 1967).
Rudman, J. of Clinical Invest. 50, pp.90-96, (1971).
Parthasarathy et al., Canad. J. of Biochem., vol. 42, 1964 pp. 377-384.

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