Therapeutic compositions based on 1,2-dithiole-3-thione derivati

Details Therapeutic compositions based on 1,2-dithiole-3-thione derivati Therapeutic compositions based on 1,2-dithiole-3-thione derivati

1995-11-27

1998-05-12

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

A61K 31385

Patent

active

057505608

ABSTRACT:
The present invention relates to therapeutic compositions based on compounds chosen from the formulae: ##STR1## in which: X is chosen from .dbd.S, .dbd.O, .dbd.SO, .dbd.N--OH, .dbd.N--R.sub.5, .dbd.N--NH--CONH.sub.2, .dbd.N--NH--CSNH.sub.2 and ##STR2## A is chosen from the >C.dbd.N--OH group, a group of formula >C.dbd.N--OR.sub.3, a C.dbd.O group, a group C.dbd.N--R.sub.4 and a CHOH group,
and their pharmaceutically acceptable salts.
These compositions may be used as free-radical trapping agents.

REFERENCES:
Faust, CA 67:82141s (1967).
Stachel, CA 114:164074a (1991).

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