Therapeutic compositions

Details Therapeutic compositions Therapeutic compositions

2007-07-31

2007-07-31

Zucker, Paul A. (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

C530S332000

Reexamination Certificate

active

10841950

ABSTRACT:
A method is provided for the preparation of compounds of the formula (R1)(R2)NC(═X)S(O)nR3or (R1)(R2)NC(═X)OS(O)nR3, wherein R1, R2and R3, X and n have any of the meanings defined in the specification. A method is also provided for the detection and quantitation of compounds of the formula (R1)(R2)NC(═X)OS(O)nR3. A method to link a therapeutic agent to a compound that is conjugated to glutathione is also provided for the purpose of improving the therapeutic properties of the therapeutic agent. Novel compounds, intermediates, pharmaceutical compositions and methods of use are also provided.

REFERENCES:
patent: 6156794 (2000-12-01), Faiman et al.
patent: WO-98/19676 (1998-05-01), None

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