Therapeutic composition

Drug – bio-affecting and body treating compositions – Bleach for live hair or skin

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424DIG3, 424338, A61K 7135

Patent

active

040566110

ABSTRACT:
The therapeutic composition is for the treatment of acne and comprises a stable dispersion of finely divided particles of benzoyl peroxide in an aqueous alcohol vehicle having a single phase, said phase being non-lipid and containing a non-ionic surface active agent that is soluble in the aqueous alcohol vehicle of the composition. The composition comprises from about 1 to 30 percent by weight benzoyl peroxide, from about 1 to 30 percent by weight of said surface active agent, from about 10 to 80 percent by weight of an alkyl alcohol having from 1 to 3 carbon atoms, and from about 10 to 80 percent by weight of water. The hydrophilic portion of the surface active agent is a polyoxyalkylene moiety wherein each oxyalkylene group contains from 2 to 3 atoms, and preferably is polyoxyethylene lauryl ether.

REFERENCES:
patent: 1838707 (1931-12-01), Rutzler, Jr. et al.
patent: 2218172 (1940-10-01), Kokatnur
patent: 2542898 (1951-02-01), Brown et al.
patent: 3530217 (1970-09-01), White et al.
patent: 3535422 (1970-10-01), Cox et al.
Pharmaceutical Formulas, 1947, vol. 2, pp. 76 & 94, RS 125 P 45.
Pharmaceutical Formulas, 1954, vol. I, pp. 55, 845&853.
U.S. Dispensatory, 1955, Part I, pp. 1308-1311.

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