Therapeutic combination of a VEGF antagonist and...

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

Reexamination Certificate

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Details

C424S192100, C514S002600, C514S012200, C530S350000, C536S023400

Reexamination Certificate

active

07449182

ABSTRACT:
Disclosed are compositions and methods for treating a disease or condition related to angiogenesis with a vascular endothelial growth factor (VEGF) inhibitor and one or more anti-hypertensive agent(s). The method of the invention is useful for preventing the development of hypertension and/or reducing hypertension in a subject treated with a VEGF inhibitor.

REFERENCES:
patent: 6897294 (2005-05-01), Davis-Smyth et al.
patent: 2003/0144298 (2003-07-01), Curwen et al.
patent: WO 2004/110490 (2004-12-01), None
patent: WO 2005/000895 (2005-01-01), None

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