Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai
Patent
1986-10-24
1990-10-16
Rollins, John W.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Carbohydrate doai
514855, 514934, A61K 3170
Patent
active
049635336
ABSTRACT:
The present invention relates to a composition containing the compound 2', 3'-dideoxycytidinene which has an antiviral effect against human immunodeficiency virus (HIV) and may therefore be used as a therapeutic agent for the treatment of AIDS and AIDS related diseases.
REFERENCES:
patent: 4704357 (1987-11-01), Mitsuya et al.
Hamamoto et al, The Chemical Abstracts, 107: 70319n (1987).
Mitsuya et al, Proc. Nat. Acad. Sci., USA, 82, 7096-7100 (1985).
Mitsuya et al, Proc. Nat. Acad. Sci., USA, 83, 1911-1915 (1986).
Mitsuya et al, "AIDS-Modern Concepts and Therapeutic Challenges".
Letter by F. Brown in Science Magazine.
Horwitz et al, Tetrahedron Letters, No. 38, pp. 2725-2727, 1964.
Horwitz et al, Tetrahedron Letters, No. 13, pp. 1343-1346, 1966.
Horwitz, et al, Journal of Organic Chemistry, 32, pp. 817-818.
European Patent Application 0 265 595 published Mar. 30, 1988.
Balzarini Jan M. R.
Broder Samuel
De Clercq Erik D. A.
Herdewijn Piet A. M. M.
Rollins John W.
Stichting Rega VZW (REGA)
The Government of the United States of America
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