Therapeutic application of chimeric and radiolabeled antibodies

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Structurally-modified antibody – immunoglobulin – or fragment...

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4241431, 4241441, 4241531, 4241551, 4241731, 4241741, 424 149, 424800, 424801, 424 937, 5303873, 53038822, 53038873, 5303888, 5303897, 5303913, 530804, 530867, 435328, 435334, 4353431, 435344, 435354, A61K 3900, A61K 39395, A61K 5100, C07K 1630

Patent

active

058434399

ABSTRACT:
Disclosed herein are therapeutic treatment protocols designed for the treatment of B cell lymphoma. These protocols are based upon therapeutic strategies which include the use of administration of immunologically active mouse/human chimeric anti-CD20 antibodies, radiolabeled anti-CD20 antibodies, and cooperative strategies comprising the use of chimeric anti-CD20 antibodies and radiolabeled anti-CD20 antibodies.

REFERENCES:
patent: 5500362 (1996-03-01), Robinson et al.
Anderson et al., The Second Annual IBC Int. Conference on Antibody Engineering, Dec. 16-18, 1991.
Grosshard et al., Blood, 80:863-878, 1992.

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