Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1989-05-19
1992-07-21
Dees, Jose G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514650, 514648, 548257, A61K 3141
Patent
active
051323150
ABSTRACT:
Tumor invasion and metastasis is the most life threatening aspect of cancer. Invasion and metastasis is a multistep process. Cellular functions required for invasion are attachment, locomotion and directed migration. Regulation of these processes may be independent of cell growth. A carboxylamino-imidazole compound was found to be potent inhibitor of tumor cell attachment, motility, invasion, proliferation, and metastasis. This compound and equivalents thereof constitute a cancer treatment agent of particular use in the treatment of peritoneal carcinomatosis of ovarian cancer.
REFERENCES:
patent: 4847257 (1962-10-01), Hupe et al.
Darland's Illustrated Medical Dictionary, 26th Ed., pp. 806, 805, 1985.
Kohn Elise C.
Liotta Lance A.
Carr Deborah D.
Dees Jos,e G.
The United States of America as represented by the Department of
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