Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Conjugate or complex
Patent
1994-04-08
1995-12-05
Rollins, John W.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Conjugate or complex
514926, 514927, 514928, A61K 3578
Patent
active
054726956
ABSTRACT:
The invention relates to the use of either an aqueous extract or an organic extract of the plant Thymus to prepare a pharmaceutical composition useful to inhibit the growth of Helicobacter pylori and the urease activity of Helicobacter pylori. In case of an aqueous extract, a minimum amount of 0.5 mg of the dry plant in the extract is required but the preferred amounts are above 1.2 mg. The aqueous extract may be used either as a drink, with or without additional ingredients, or transformed into a capsule or a paste. The invention also relates to in-vitro methods for inhibiting the growth of the urease activity of Helicobacter pylori.
REFERENCES:
patent: 4803069 (1989-02-01), Kekesi et al.
patent: 5252344 (1993-10-01), Shi
H. G. Desai et al., "Dental Plaque: A Permanent Reservoir of Helicobacter pylori?" Scand J. Gastroenterol, 26, 1991, pp. 1205-1208.
K. Rosberg, "Adhesion of Helicobacter pylori to Human Gastric Mucosal Biopsy Specimens Cultivated in Vitro," Scand. J. Gastroenterol, 26, 1991, pp. 1179-1187.
Laura L. Zaika, "Spices and Herbs: Their Antimicrobial Activity and Its Determination," Journal of Food Safety, Sep. 1988, pp. 97-118.
Enno Hentschel et al., "Effect of Ranitidine and Amoxicillin Plus Metronidazole on the Eradication of Helicobacter Pylori and the Recurrence of Duodenal Ulcer", The New England Journal of Medicine, vol. 328, No. 5, pp. 308-312.
David Y. Graham, M.D., "Treatment of Peptic Ulcers Caused by Helicobacter Pylori", The New England Journal of Medicine, vol. 328, No. 5, pp. 349-350.
Walter L. Peterson, M.D., "Helicobacter Pylori and Peptic Ulcer Disease", The New England Journal of Medicine, vol. 324, No. 15, pp. 1043-1047.
Y. Glupczynski, "Use of a Urea Breath Test versus Invasive Methods to Determine the Prevalence of Helicobacter Pylori in Zaire", Eur. J. Clin. Microbiol. Infect. Dis., Apr. 1992, vol. 11, No.4, pp. 322-326.
C. Lens-Lisbonne et al., Chem. Abstract, 108:52692v, vol. 108, 1988.
A. Pizsolitto et al., Chem. Abstract, 86:12226s, vol. 86, 1977.
S. Gocho, Chem. Abstract, 116:37816k, vol. 116, 1992.
Armon Robert
Neeman Itzhak
Tabak Mina
Rollins John W.
Technion Research and Development Foundation Ltd.
LandOfFree
Therapeutic application of a thyme extract and in - vitro method does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic application of a thyme extract and in - vitro method, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic application of a thyme extract and in - vitro method will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1372279