Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1996-10-22
1998-12-29
Huff, Sheela
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
530326, 435 691, 435 723, A01N 6100, A61K 3800, C12P 2106, G01N 33574
Patent
active
058542051
ABSTRACT:
Isolated endostatin protein that is an inhibitor of endothelial cell proliferation and angiogenesis. Endostatin protein has a molecular weight of approximately 18 kDa as determined by non-reducing gel electrophoresis or approximately 20 kDa as determined by reducing gel electrophoresis. Endostatin protein corresponds to a C-terminal fragment of collagen type XVIII, and the protein can be isolated from the murine hemangioendothelioma EOMA cell line.
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Folkman M. Judah
O'Reilly Michael S.
Eyler Yvonne
Huff Sheela
The Children's Medical Center Corporation
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