Therapeutic anti-cytomegalovirus compounds

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 8 to 10 amino acid residues in defined sequence

Reexamination Certificate

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Details

C424S186100, C424S184100, C424S230100, C435S002000, C435S007100, C435S007210, C530S326000, C530S327000

Reexamination Certificate

active

10434982

ABSTRACT:
The present invention provides synthetic compounds, antibodies that recognize and bind to these compounds, polynucleotides that encode these compounds, and immune effector cells raised in response to presentation of these epitopes. The invention further provides methods for inducing an immune response and administering immunotherapy to a subject by delivering the compositions of the invention.

REFERENCES:
Zugel et al. Termination of peripheral tolerance to a T cell epitope by heterolitic antigen analogues. The Journal of Immunology, 1998, 1706-1709.
Chen et al. Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL. The Journal of Immunology, 2000, 948-955.
Miltenyi Biotec's CMV pp65-recombinant protein human cytomegalovirus, 2006.
Chen, Ji-Li et al., “Identification of NY-ESO-1 Peptide Analogues Capable of Improved Stimulation of Tumor-Reactive CTL”, The Journal of Immunology, 2000, 165:948-955.
Zugel, Ulrich et al., “Termination of Peripheral Tolerance to a T Cell Epitope by Heteroclitic Antigen Analogues”, The Journal of Immunology, 1998, 161:1705-1709.

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