Therapeutic and diagnostic methods using leukocyte surface antig

Details Therapeutic and diagnostic methods using leukocyte surface antig Therapeutic and diagnostic methods using leukocyte surface antig

1990-11-07

1995-06-20

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 724, 435 79, 435 794, 436501, 436506, 436518, 436536, G01N 33536, G01N 33543

Patent

active

054260299

ABSTRACT:
The present invention is directed to the measurement of soluble leukocyte surface markers, soluble T cell growth factor receptors, soluble complement receptors, soluble T cell differentiation antigens, or related soluble molecules or fragments thereof, and the use of such measurements in the diagnosis and therapy of diseases and disorders. The invention is also directed to the measurement of soluble CD35 (sCD35) or fragments thereof, and the use of such measurements in detecting disease or disorders. A polyclonal sandwich assay is provided for the detection and/or measurement of soluble CD35. The invention further relates to the measurement of total leukocyte markers or fragments thereof, and the use of such measurements in the detection and diagnosis of diseases or disorders. The term "total" leukocyte marker used herein refers to the total amount of a leukocyte marker in a sample, including that present in membrane and intracellular compartments and extracellular soluble compartments. Measurements of a total leukocyte marker can be used to determine the approximate amount in a body fluid sample of leukocytes positive for the leukocyte marker. In a further embodiment, the invention relates to the measurement of both the amount of total leukocyte marker and the amount of the soluble form of the leukocyte marker and a comparison of the measured levels.

REFERENCES:
patent: 4376110 (1983-03-01), David et al.
patent: 4707443 (1987-11-01), Nelson et al.
patent: 4810632 (1989-03-01), McMillan
patent: 4845026 (1989-07-01), Kung et al.
patent: 5006459 (1991-04-01), Kung et al.
patent: 5059524 (1991-10-01), McKenzie et al.
patent: 5100777 (1992-03-01), Chang
patent: 5168044 (1992-12-01), Joyce et al.
M. G. Scott et al, Trends in Biotechnol., 3, 170-175, 1985.
S. H. Yoon et al, Journ. Immunol., 134, 3332-3338, 1985.
Berthier et al., "Lymphocyte Surface Molecules in Healthy or HIV Infected Children and Adults" and Capcellia CD4/CD8 Kit for the Immunoassay of CD4/CD8 markers, Diagnostics Pasteur product literature, 1990.
Chem Abstracts, vol. 113 No. 9, 27 Aug. 1990.
Weisman et al. (1990, Science 249:146-151).
Weis et al. (1987, J. Immunol 138:312-315).
Wong et al. (1985, Proc. Natl. Acad. Sci. U.S.A. 82:7711-7715).
Sim (1985, Biochem. J. 233:883-889).
Dykman et al. (1983, Proc. Natl. Acad. Sci. U.S.A. 80:1698-1702).
Iida et al. (1982, J. Exp. Med. 155:142-1438).
Fearon (1979, Proc. Natl. Acad. Sci. U.S.A. 16:5867-5871).
Kung et al., Science 206:347-349 (1979).
Reinherz et al, Proc. Natl. Acad. Sci. U.S.A. 76:4061-4065 (1979).
Reinherz et al., Proc. Natl. Acad. Sci. U.S.A. 77:1588-1592 (1980).
Verbi et al., Eur. J. Immunol. 12:81-86 (1982).
Kanellopoulos et al., The EMBO J. 2:1807-1814 (1983).
Kung et al., Int. of Dermatol. 22:67-74 (1983).
Krensky and Clayberger, Transplantation 39:339-348 (1985).
McDougal et al., Science 231:382-385 (1986).
Miller et al., Bood 58(1):78-86 (1981).
Falcao et al., J. Clin. Lab. Immunol. 13:141-143 (1984).
Oh et al., Scan. J. Immunol. 22:51-60 (1985).
Acuto et al., Cell 34:717-726 (1983).
Brenner et al., J. Exp. Med. 160:541-551 (1984).
Meuer et al., Proc. Natl. Acad. Sci. U.S.A. 81:1509-1513. (1984a).
Meuer et al., Ann. Rev. Immunol. 2:23-50 (1984b).
McKenzie and Parish, J. Exp. Med. 144:847-851 (1976).
Parish et al., Immunogenetics 3:129-137 (1976).
Parish and McKenzie, Cellular Immunol. 33:134-144 (1977).
Parish et al, Infection and Immunity 26:422-426 (1979).
Wilson et al., J. Immunol. 122:1967-1971 (1979).
Sandrin et al., J.N.C.I. 66:279-283 (1981).
Mier and Gallo, Proc. Natl. Acad. Sci. U.S.A. 77:6134-6138 (1980).
Smith, Immunol. Rev. 51:337-357 (1980).
Arya et al., Science 233:1086-1087 (1984).
Lotze et al., J. Immunol. 135:2865-2875 (1985).
Touw et al., Blood 66:556-561 (1985).
Robb et al., J. Exp. Med. 154:1455-1474 (1981).
Uchiyama et al., J. Immunol. 126:1393-1397 (1981).
Leonard et al., Nature 300:267-269 (1982).
Korsmeyer et al., Proc. Natl. Acad. Sci. U.S.A. 80:4522-4526 (1983).
Depper et al., J. Immunol. 133:1691-1695 (1984).
Sugamura et al., Proc. Natl. Acad. Sci. U.S.A. 81:7441-7445 (1984).
Tsudo et al., J. Expl. Med. 160:612-617 (1984).
Waldman et al., J. Exp. Med. 160:1450-1466 (1984).
Dower et al., J. Exp. Med. 162:501-515 (1985).
Ebert et al., Clin Immunol. and Immunopathol. 37:283-297 (1985).
Rubin et al., Hybridoma 4:91-102 (1985).
Uchiyama et al., J. Clin. Invest. 76:446-453 (1985).
Greene and Leonard, Ann. Rev. Immunol. 4:69-95 (1986).
Gupta, Clin. Immunol. and Immunopathol. 38:93-100 (1986).
Mutsuoka et al., Leukemia Res. 10:597-603 (1986).
Tsudo et al., Blood 67:316-321 (1986).
Tuow et al., Blood 68:1088-1094 (1986).
Chilosi, et al., Int. J. Biological Markers 2:101-104 (1986).
Durno et al., Blood 68 Suppl. #1,124a (1986).
John et al., Sixth Int. Cong. Immunol. Toronto, Canada (1986).
Keller et al., Am. Diabetes Assoc. (1986).
Nelson et al., Pediatric Res. 20:136-139 (1986).
Pizzolo et al., Blood 68 Suppl. #1, 228a (1986).
Reuben et al., Blood 68 Suppl. #1, 213a (1986).
Rubin et al., J. Immunol. 137:3841-3844 (1986).
Saadeh et al., Fed. Proc. 45:378 (1986).
Treiger et al., J. Immunol. 136:4099-4105 (1986).
van Es et al., Transplantation 37:65-69 (1984).
Austen and Cosimi, N. Engl. J. Med. 311:1436-1438 (1984).
Hancock et al., Transplantation 39:430-438 (1985).
Magrath et al., Blood 63:1102-1111 (1984).
Pui et al., Blood 66:778-782 (1985).
Murphy et al., J. Clin. Oncol. 4:1732-1739 (1986).
Arseneau et al., Am.J.Med. 58:314-321.
Gay et al., Nature 328:626-629, (1987).
Dagleish et al., Immunol. Today 7:142-143 (1986).
Sattentau et al., Cell 52:631-633, (1988).
Fisher et al., Nature 331:76-78, (1988).
Germain et al., Cell 54:441-444, (1988).
Weiss et al., Nature 331:15, (1988).
Siliciano et al., Cell 54:561-575, (1988).
Hussey et al., Nature 331:78-81, (1988).
Maddon et al., Cell 42:93-104, (1985).
Littman et al., Nature 325:453-455, (1987).
Traunecker et al., Nature 331:84-86, (1987).
Smith et al., Science 238:1704-1707, (1987).
Maddon et al., PCT International Publication No. WO88/01304 published Feb. 25, 1988.
Deen et al., Nature 331:82-84, (1988).
Doyle et al., Nature 330: 256-259, (1987).
Booth et al., News & Comment, Science 239:341-343, (1988).
Meuer et al., Proc. Natl. Acad Sci USA 79:4395-4399, (1982).
Biddison et al., J. Exp. Med. 159:783, (1984).
Hoxie et al., J. Immunol, 137:1194-1201, (1986).
Snow et al., J. Biol. Chem. 258:14675-14681, (1983).
Doumerc et al., 1986 6th Intl. Congress of Immunology, Toronto, Ontario, Canada, Jul. 1986, Abstr. 5.54.6, p. 768.
Kung et al., Clin. Chem. 34:1340 (1988).
Swain et al., Proc. Natl. Acad. Sci. U.S.A. 78:7101-7105 (1981).
Francus et al., J. Immunol. 140:1823-1829 (1988).
Greene et al., Ann. Intern. Med. 105:560-572 (1986).
Rubin et al., in Leukocytes and Host Defense, Oppenheim, J. J., and D. M. Jacobs, eds., Alan R. Liss, Inc., New York, pp. 95-120, (1986).
Yasuda et al., Blood 71:1021-1026 (1988).
Steis et al., Blood 71:1304-1309 (1988).
Pui et al., Blood 71:1135-1137 (1988).
Wolf et al., Arth. Rheum. 31:729-735 (1988).
Stolc et al., Diag. Clin. Immunol. 5:171-174 (1987).
Tomkinson et al., J. Immunol. 139:3802-3807 (1987).
Rubin et al., vol. 104 No. 21, p. 489 abstract No. 184611, (May 26, 1986).
Cerretti et al., EP-A-0 162 699, Immunex Corp., (1985).
Nelson et al., EP-A-O 202 975 (The United States of America), (1986).
Rubin et al., (1985), Federation Proceedings, 69th Annual Mtg., Anaheim Calif., vol. 44, No. 4, Apr. 21-26, 1985, Abstract 3131, pp. 946, Mar. 5, 1985.
Fujimoto et al., J. Exp. Med. 160:116-124, Jul. 1984.
Snow et al., The Journal of Biological Chemistry 260:2700-2708 (1985).
Snow et al., The Journal of Immunology 135:3172-3177, (Nov. 1985).
Rubin et al., The Journal of Immunology 135:3172-3177, Nov. 1985.
Rubin et al., Clin Research, vol. 33, No. 2, p. 388A, (Apr. 1986).
Osawa et al., Eur. J. Immunol., :467-469, (1986).
Nelson et al., Journal of Clinical Immunology 6:114-120, (1986).
Bayer et al., DT, A, 3628718, (Jun. 4, 1987).
Nelson et al., U.S. Patent No. 4,707,443, (1987).
Kung et al.., WO A, 8705912, PCT, (Oct. 8, 1987).
Mackeen et al., Fed. Proc., 45:457, A

Affiliated with

Also associated with

Rating

Therapeutic and diagnostic methods using leukocyte surface antig does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Therapeutic and diagnostic methods using leukocyte surface antig, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic and diagnostic methods using leukocyte surface antig will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1843693