Therapeutic agents in the form of submicroscopic particles again

Details Therapeutic agents in the form of submicroscopic particles again Therapeutic agents in the form of submicroscopic particles again

1987-10-07

1989-07-04

Schofer, Joseph L.

Drug, bio-affecting and body treating compositions

Lymphokine

A61K 3178

Patent

active

048449008

ABSTRACT:
The invention relates to new therapeutic agents against Leishmaniasis.
These therapeutic agents consist of submicroscopic particles whose diameter is less than 500 nanometers, the particles being obtained by the micellar polymerization of an alkyl cyanoacrylate in which the alkyl chain contains from 1 to 12 carbon atoms.
The therapeutic agents according to the invention may be administered parenterally.

REFERENCES:
patent: 4186183 (1980-01-01), Steck et al.
patent: 4489055 (1984-12-01), Couvreur et al.
Chemical Abstracts, vol. 98, No. 21, May 23, 1983, p. 364, No. 185458v, Columbus, Ohio, US; J. Kreuter.
Chemical Abstracts, vol. 104, No. 20, May 19, 1986, p. 384, No. 174575x, Columbus, Ohio, US; M. S. El-Samaligy et al.
Chemical Abstracts, vol. 105, No. 21, Nov. 24, 1986, p. 404, No. 187450y, Columbus, Ohio, US; L. Golightly et al.
Chemical Abstracts, vol. 72, No. 5, Feb. 2, 1970, p. 174, No. 20279n, Columbus, Ohio, US; L. M. Gordeeva et al.
Chemical Abstracts, vol. 73, 1970, p. 226, No. 129274d, Columbus, Ohio, U.S.; P. J. Van Dijck et al.

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