Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1977-08-01
1978-10-17
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
424246, 42424856, 544 51, 544 52, 544 58, 544 62, 544105, 544116, 544237, 544235, 260154, 260155, 260157, 260165, 260152, 260158, 260162, 544353, 544283, C07D23732, A61K 3150, C07D41704
Patent
active
041209605
ABSTRACT:
Therapeutic activity, and in particular the ability to induce diuresis or saluresis, has been discovered in 4-hydroxy- or 4-mercapto-2-aryl-1,2-dihydrophthalazine-1-acetic acids, the tautomers of these namely 4-oxo or thio-2-aryl-1,2-tetrahydrophthalazine-1-acetic acids, and in the ester and alcohol derivatives of the acids, and in the acyl derivatives of the 4-hydroxy or mercapto compounds and in the 3-alkyl derivatives of the 4-oxo or thio compounds. Therapeutic compositions and methods using the compounds are described, as also are novel compounds.
REFERENCES:
patent: 3497512 (1970-02-01), Hofer et al.
patent: 3833579 (1974-09-01), Inoue et al.
patent: 3870792 (1975-03-01), Inoue et al.
patent: 3963716 (1976-06-01), Inoue et al.
Rowe et al.; J. Chem. Soc. (London) pp. 461-468 (1947).
Rowe et al.; J. Chem. Soc. (London) pp. 829-833 (1947).
Puodzuinas et al.; Chem. Abs. vol. 79: 137066b (1973).
Jaecklin et al.; Chem. Abs. vol. 76: 85263e (1972).
Simpson; The Chemistry of Heterocyclic Compounds Chap. XIV, pp. 106-118 (1953).
Foldeak et al.; Chem. Abs. vol. 73: 77173y (1970).
Bristow Norman W.
Macey Peter E.
Nichol Kenneth J.
Sim Malcolm F.
Daus Donald G.
Hueschen Gordon W.
The Boots Company Limited
Vaughn Mary C.
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