Therapeutic Agents

Details Therapeutic Agents Therapeutic Agents

2007-02-02

2008-08-05

Davis, Brian J (Department: 1621)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Nitrogen containing other than solely as a nitrogen in an...

C564S339000

Reexamination Certificate

active

07407990

ABSTRACT:
Substituted cycloalkyl compounds with 3 to 6 carbon atoms in the ring, one carbon linked to each of two side groups R and R′, and pharmaceutically acceptable salts thereof in which R is phenyl optionally substituted by one or more halo substituents or R is naphthyl; and R′ is —[X—Y—S(O)m-Z-N—R1—R2], wherein X is carbonyl or a carbon directly linked to each of a hydroxyl group and R5in which R5is H or alkyl, Y is an alkylene chain optionally substituted by one or more alkyl groups, m can be 0, 1 or 2, Z is an alkylene chain containing 2 to 5 carbon atoms optionally substituted by one or more alkyl groups, and R1and R2, which are the same or different, are H, alkyl, or arylalkyl, provided that when R1is benzyl, R2is H or methyl; have utility in the treatment of drug misuse or other addictive disorders.

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patent: WO 98/29411 (1998-07-01), None

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