Therapeutic agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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C564S339000

Reexamination Certificate

active

06974840

ABSTRACT:
Compounds of formula (I) and pharmaceutically acceptable salts thereof in which m is 0, 1 or 2; n is 2, 3, 4 or 5; X is carbonyl or a group of formula (II) in which R5is H or alkyl; Y is an alkylene chain optionally substituted by one or more alkyl groups; Z is an alkylene chain containing 2 to 5 carbon atoms optionally substituted by one or more alkyl groups; R is phenyl optionally substituted by one or more halo substituents or R is naphthyl; and R1and R2, which are the same or different, are H, alkyl, or arylalkyl, provided that when R1is benzyl, R2is H or methyl; have utility in the treatment of drug misuse or other addictive disorders.

REFERENCES:
patent: 5047432 (1991-09-01), Housley et al.
patent: 0 111 994 (1983-09-01), None
patent: 0 282 206 (1990-11-01), None
patent: 2 098 602 (1981-04-01), None
patent: 94/26704 (1994-11-01), None
patent: WO 95/2327 (1995-10-01), None
patent: WO 98/29411 (1998-07-01), None
Database CAPLUS on STN, Acc. No. 1995:380315, Harris et al., WO 9426704 (abstract).

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