Therapeutic agent for wounds and screening method for the same

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Carbohydrate doai

Reexamination Certificate

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Details

C536S024310, C536S024100, C536S024500

Reexamination Certificate

active

07960363

ABSTRACT:
The present invention provides an agent for treating wound, containing a substance that suppresses the expression or function of PDLIM2. The substance that suppresses the expression or function of PDLIM2 is preferably an siRNA or antisense nucleic acid capable of specifically suppressing the expression of PDLIM2, or an expression vector capable of expressing said polynucleotide. In addition, the present invention provides a method of screening for a substance capable of treating wounds, including determining whether or not a test substance is capable of suppressing the expression or function of PDLIM2.

REFERENCES:
patent: 2006/0177906 (2006-08-01), O'Connor et al.
patent: 2006/0246543 (2006-11-01), Grusby et al.
patent: 2007-254465 (2007-10-01), None
Soutschek et al. Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs. Nature vol. 432, 2004 oo:173-178.
Tanaka et al.,Immunity, 22: 729-736 (Jun. 2005).
Tanaka et al.,Nature Immunology, 8(6): 584-591 (Jun. 2007).

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