Therapeutic agent for rheumatic disease

Details Therapeutic agent for rheumatic disease Therapeutic agent for rheumatic disease

1997-03-04

2000-07-11

MacMillan, Keith D.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Monoclonal antibody or fragment thereof

4241441, 4241431, 4241421, 4241411, 4241551, A61K 39395

Patent

active

060868775

ABSTRACT:
The present invention relates to a therapeutic agent for rheumatic disease comprising an anti-Fas monoclonal antibody, or the combination of an anti-Fas monoclonal antibody and a medical substance having an inhibitory effect of cell proliferation as an active ingredient. The anti-Fas monoclonal antibody of this invention reacts with the Fas antigen in synovial cells of patients with rheumatoid arthritis, especially the human Fas antigen specifically and expresses apoptosis on synovial cells.

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