Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Reexamination Certificate
2006-10-19
2010-10-05
Saoud, Christine J (Department: 1647)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
C514S012200, C530S399000
Reexamination Certificate
active
07807628
ABSTRACT:
The present invention provides a therapeutic agent for regenerating a dentin-pulp complex, containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient. The present invention also provides a pulp-capping agent containing a basic fibroblast growth factor and/or a homolog thereof as an active ingredient.
REFERENCES:
patent: 6046164 (2000-04-01), Asano et al.
patent: 6831058 (2004-12-01), Ikada et al.
patent: 2005/0142076 (2005-06-01), Fukunaga et al.
patent: 0 702 959 (1996-03-01), None
patent: 1 498 135 (2005-01-01), None
patent: 6-340555 (1994-12-01), None
patent: 7-17876 (1995-01-01), None
patent: 94/27630 (1994-12-01), None
patent: 03/082321 (2003-10-01), None
Roberts-Clark et al. Arch. Oral Biol. 45: 1013-1016, 2000.
M. Nakashima, “The efffects of growth factors on DNA synthesis, proteoglycan synthesis and alkaline phosphatase activity in bovine dental pulp cells”, Archs Oral Biol. vol. 37, No. 3, pp. 231-236 (1992).
Kazuhisa Nakao et al., “FGF-2 potently induces both proliferation and DSP expression in collagen type I gel cultures of adult incisor immature pulp cells”, Biochemical and Biophysical Research Communications, vol. 325, pp. 1052-1059 (2004).
Toshihiko Takase, “A Histopathological Study of α-tricalcium Phosphate Cement Containing Growth Factor as Direct Pulp Capping Agent”, Dept. of Endodontics, Nihon University School of Dentistry at Matsudo, vol. 25, pp. 415-426 (1999)—English language abstract at p. 426.
Supplementary European Search Report issued Aug. 27, 2009 in corresponding European Patent Application No. 06 82 2285.
Kadokura, H. “Effects of Basic FGF on Differentiation of Odontoblast-like Cells in Rat Dental Pulp Cells”, Japanese Journal of Conservative Dentistry, Nihon Shika Hozon Gakkai, Tokyo, JP, vol. 45, No. 1, Jan. 1, 2002, pp. 106-118, XP003012053.
Hu et al. “Reparative Dentin Formation in Rat Molars after Direct Pulp Capping with Growth Factors”, Journal of Endodontics, Lippincott, Williams & Williams, Philadelphia, PA, US, vol. 24, No. 11, Nov. 1, 1998, pp. 744-751, XP022196217.
Tziafas, D. et al. “Effects of Recombinant Basic Fibroblast Growth Factor, Insulin-like Growth Factor-II, and Transforming Growth Factor—β1on Dog Dental Pulp Cells in Vivo”, Archives of Oral Biology, vol. 43, No. 6, Jun. 1998, pp. 431-444, XP002540239.
Shiba, Hideki et al. “Effects of Basic Fibroblast Growth Factor on Proliferation, the Expression of Osteonection(SPARC)and Alkaline Phosphatase, and Calcification in Cultures of Human Pulp Cells”, Developmental Biology, vol. 170, No. 2, 1995, pp. 457-466, XP002540240.
Murakami Shinya
Shimabukuro Yoshio
Kaken Pharmaceutical Co. Ltd.
Osaka University
Saoud Christine J
Wenderoth , Lind & Ponack, L.L.P.
LandOfFree
Therapeutic agent for dentin-pulp complex regeneration does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Therapeutic agent for dentin-pulp complex regeneration, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Therapeutic agent for dentin-pulp complex regeneration will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4210991