Therapeutic 1H-pyrido [4,3-b] indoles

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S291000, C514S228200, C514S232800, C546S086000, C546S085000, C544S060000, C544S128000

Reexamination Certificate

active

06849640

ABSTRACT:
The present invention provides 2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles and 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. These compounds are 5-HT ligands that are useful for treating diseases wherein modulation of 5-HT activity is desired.

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“Synthesis of 2,3,4,4a,5,9b-Hexahydro-1H-pyrido [4,3-b] indole Derivatives and Their Central Nervous System Activities”, by Yasutaka Nagai et al, Journal of Medicinal Chemistry, American Chemical Society, vol. 22, No. 6, 1979, pp. 677-683.

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