Theophyllinyl-alkyl-oxadiazoles, process for the preparation the

Details Theophyllinyl-alkyl-oxadiazoles, process for the preparation the Theophyllinyl-alkyl-oxadiazoles, process for the preparation the

1983-03-11

1986-01-21

Rizzo, Nicholas S.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

544269, 544267, 544138, 544364, C07D47310, A61K 3152

Patent

active

045658170

ABSTRACT:
Antitussive compounds of the formula I ##STR1## or physiologically acceptable acid addition salts thereof are disclosed, where A stands for straight or branched chain C.sub.1-5 alkylene or ##STR2## R.sub.1 stands for straight or branched chain C.sub.1-10 alkyl, halogenoalkyl, hydroxyalkyl, C.sub.5-6 cycloalkyl, vinyl, 2-ethoxyethyl, carbonylalkyl or aminoalkyl of the formula ##STR3## wherein R stands for hydrogen or methyl, n is 0 to 3,

REFERENCES:
patent: 3280122 (1966-10-01), Hasanyi et al.
patent: 3459753 (1969-08-01), Boltze et al.
patent: 4197300 (1980-04-01), Scagini et al.
patent: 4378359 (1983-03-01), Chiodoni et al.
J. Chem. Res. (M), 1979, 0801-0809.
Arch. Exp. Path. Pharmacol., 195, 71 (1940).

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