Theophylline salts of 5-methylisoxazole-3-carboxylic acid

Details Theophylline salts of 5-methylisoxazole-3-carboxylic acid Theophylline salts of 5-methylisoxazole-3-carboxylic acid

1976-12-08

1978-05-30

Coughlan, Jr., Paul M.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

544269, A61K 3152, C07D47308

Patent

active

040924173

ABSTRACT:
The salts of N-unsubstituted, N-monosubstituted and N,N-disubstituted 7-(3-amino-2-hydroxypropyl)theophylline and 5-methylisoxazole-3-carboxylic acid are hypolipidaemic agents. The compounds, of which the 7-[3-(N-methyl-N-2-hydroxyethyl)amino-2-hydroxypropyl]-theophylline salt of 5-methylisoxazole-3-carboxylic acid is a representative embodiment, are prepared by allowing the isoxazole acid and the amine to react.

REFERENCES:
patent: 2924598 (1960-02-01), Bestian et al.
patent: 3801578 (1974-04-01), Harsanyi et al.
patent: 3980646 (1976-09-01), Brenner et al.

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