Theophylline immunogens, antibodies, labeled conjugates, and rel

Details Theophylline immunogens, antibodies, labeled conjugates, and rel Theophylline immunogens, antibodies, labeled conjugates, and rel

1981-08-27

1985-08-06

Schain, Howard E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260112R, 260121, 424 85, 435 7, 435188, C07G 700, C07G 702

Patent

active

045334935

ABSTRACT:
Theophylline immunogens, antibodies prepared therefrom, labeled theophylline conjugates, synthetic intermediates, and the use of such antibodies and labeled conjugates in immunoassays for determining theophylline. The immunogens comprise theophylline coupled at its 9-position to an immunogenic carrier material. Likewise, the labeled conjugates and synthetic intermediates are 9-position derivatives of theophylline or synthetic precursors thereof. The antibody and labeled reagents are particularly useful in homogeneous nonradioisotopic immunoassays for measuring theophylline in biological fluids such as serum.

REFERENCES:
patent: 4230805 (1980-10-01), Singh et al.
patent: 4279992 (1981-07-01), Boguslaski et al.
patent: 4302438 (1981-11-01), Zectt
patent: 4460772 (1984-07-01), Benovic et al.

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