Theophylline derivatives

Details Theophylline derivatives Theophylline derivatives

1983-03-11

1986-07-29

Rizzo, Nicholas S.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544268, 544269, C07D47308, A61K 3152

Patent

active

046032045

ABSTRACT:
New derivatives of theophylline having the formula ##STR1## in which R denotes hydrogen or OH, n the numbers 0 or 1, X either >CH-- or >N--, Y either --O-- or --CO-- and R a five membered or six membered aryl ring or hetero-aryl ring, that is substituted in given cases with halogen, short chain alkyl groups, alkoxy groups or halogen-alkyl, and exhibit in addition to other properties, histamine-, serotinine- bradykynine- antagonistic, anti-anaphylactic and -adrenergic stimulating effects.

REFERENCES:
patent: 3642798 (1972-02-01), Nitta et al.
patent: 4086347 (1978-04-01), Friebe et al.
patent: 4400381 (1983-08-01), Favier et al.
patent: 4548820 (1985-10-01), Legnier et al.
patent: 4548939 (1985-10-01), Dennis et al.

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