Theophylline antigens and antibodies

Details Theophylline antigens and antibodies Theophylline antigens and antibodies

1977-04-15

1979-05-22

Berch, Mark L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

195 63, 195 66R, 1951035A, 1951035R, 260112R, 544272, 528 49, 528 52, C07D47304

Patent

active

041560817

ABSTRACT:
Theophylline derivatives are provided for preparing reagents for use in competitive protein binding assays and for use as reagents in competitive protein binding assays. Theophylline is substituted at the 3 position and conjugated to antigens for production of antibodies which specifically recognize theophylline as distinct from structurally similar analogs such as caffeine. Enzyme conjugates are provided which find use for measuring the amount of theophylline in a sample suspected of containing theophylline. A method is provided employing the reagents for the determination of theophylline.

REFERENCES:
toperman et al., Chem. Abs. 68, 105/60 (1967).
Cerny et al., Chem. Abs. 64, 19610g (1966).
Bredereck et al., Chem. Ber. 1953, pp. 333-351.

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