The RESA and FIRA antigens of plasmodium falciparum

Chemistry: molecular biology and microbiology – Micro-organism – per se ; compositions thereof; proces of... – Bacteria or actinomycetales; media therefor

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435 691, 435 91, 4351723, 4352351, 536 27, 530350, 935 18, 935 31, 935 47, 935 58, 935 65, 935 73, 935 81, C12N 120, C12N 1500, C12P 2106, C12P 1934

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051262649

ABSTRACT:
DNA molecules comprising polynucleotide sequences substantially corresponding to all or a portion of the base sequence coding for an antigen of Plasmodium falciparum selected from the group consisting of the RESA antigen, the FIRA antigen, and other antigens of P. falciparum cross-reactive therewith. Such DNA molecules are capable of being expressed as polypeptide(s). Synthetic peptides or polypeptides displaying the antigenicity of all or a portion of the RESA or FIRA antigens of P. falciparum. Compositions for stimulating immune responses against P. falciparum antigens in a mammal, comprising at least one polypeptide displaying the antigenicity of the RESA or FIRA antigens of P. falciparum.

REFERENCES:
patent: 4466917 (1984-08-01), Nussenzweig et al.
Kemp, D. J. et al. Proc Nat'l Acad Sci-U.S.A. vol. 80 pp. 3787-3791 (1983).
Coppel, R. L. et al. Nature vol. 310 pp. 789-792 (1984).
Chemical Abstracts, 192681r, vol. 98, 1983, p. 170.
Proc. Natl. Acad. Sci. U.S.A. vol. 80, pp. 3787-3791, Jun. 1983, Immunology.
Chemical Abstracts, 67168g, vol. 97, 1982, p. 152.
Molecular and Biochemical Parisitology, 5 (1982), 391-400, Elsevier Biomedical Press, p. 391.
Nature, vol. 297, Jun. 17, 1982, pp. 591-593.
Antigenic Diversity in the Human Malaria Parasite Plasmodium falciparum, Science, vol. 217, Jul. 16, 1982, pp. 254-257.
Nature vol. 306, Dec. 1983, pp. 751-756.
Biochemical Abstracts, I. Cell Biochem. Suppl. 1983, vol. 0, No. 7, Part A, p. 3.
"Molecular Cloning", T. Maniattis, E. F. Fritsch, J. Sambrook, Cold Spring Harbor Laboratory 1982, pp. 17-18.
Phil. Trans. R. Soc. Lond. B. 307, 179-187 (1984) "The expression of Plasmodium falciparum bloodstage antigens in Escherichia coli".
Mol. Biol. Med. (1984) 2, 177-191, "Plasmodium falciparum complementary DNA Clones Expressed in Escherichi coli Encode many Distinct Antigens".

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