Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Reexamination Certificate
2006-06-06
2006-06-06
Nolan, Patrick J. (Department: 1644)
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
C530S327000
Reexamination Certificate
active
07057013
ABSTRACT:
Antagonistic synthetic peptides, obtained from TGFβ1 or from its receptors in the organism, that can be used in the manufacture, both on their own, as well as the gene sequences that encode them and the recombinant systems that express them, in the manufacture of compositions for use in the treatment of liver diseases and more concretely in cases of fibrosis. The said compositions can optionally include mimotopes of the said active peptides.
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patent: 5650494 (1997-07-01), Cerletti et al.
patent: 96/25178 (1996-08-01), None
Attwood, Science 2000; 290:p. 471-473.
Skolnick et al. Trends in Biotech. 2000;18(1): p. 34-39.
Metzler et al. Nature Structural Biol. 1997; 4:527-531, QH 506.N4.
Borras Cuesta Francisco
Ezquerro Saenz Ignacio José
Lasarte Sagastibelza Juan José
Prieto Valtue{overscore (n)}a Jesús
Kim Yunsoo
Ladas & Parry LLP
Nolan Patrick J.
Proyecto de Biomedicina Cima, S.L.
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