TGF-.beta. antagonists as mitigators of radiation-induced tissue

Details TGF-.beta. antagonists as mitigators of radiation-induced tissue TGF-.beta. antagonists as mitigators of radiation-induced tissue

1995-03-31

1997-04-01

Seidleck, James J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

A61K 3800

Patent

active

056165617

ABSTRACT:
A method for treating tissue damage caused by radiation is described by use of a TGF-.beta. antagonist, such as an anti-TGF-.beta. antibody or a TGF-.beta. latency associated protein. It is administered not more than a week after exposure, and is particularly useful in mitigating the side effects of breast cancer therapy.

REFERENCES:
patent: 5061786 (1991-10-01), Burnier et al.

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