Prosthesis (i.e. – artificial body members) – parts thereof – or ai – Implantable prosthesis
Patent
1989-01-31
1990-09-11
Cannon, Alan W.
Prosthesis (i.e., artificial body members), parts thereof, or ai
Implantable prosthesis
623 8, A61F 202, A61F 212
Patent
active
049559095
ABSTRACT:
Capsular contracture causing firmness of soft silicone implants is a serious problem that may result from several causative factors that have as their final pathway, the development of increased scar tissue. The present invention has altered the formation of this scar encapsulation of silicone implants by texturing the silicone surface in order to gain fibroblast ingrowth into the interstices and thus prevent micromotion at the host prosthesis interface. It has been found that this produces a thinner fibrous capsule. Previously published work pertaining to animals and man has shown that similar texturing of tetrafluoroethylene (Teflon) and other substances achieves these goals. In accordance with work leading up to the present invention, textured silicone samples have been implanted in the subcutaneous layer of rabbits, the capsule formation and the host-prosthesis interface studied histologically. A difference between the smooth surface and the textured surface could be measured wherein the textured surface had a thinner capsule without contracture and the smooth surface had a thicker capsule with contraction.
REFERENCES:
patent: 4531244 (1989-07-01), Hamas
patent: 4820303 (1989-04-01), Brauman
patent: 4889744 (1989-12-01), Quaid
McGhan, Biocel Textured Mammary Implant, 10/87.
Picha et al., Ion-Beam Microtexturing of Biomaterials, 4/84, pp. 39-42.
Beisang Arthur A.
Beisang, III Arthur A.
Ersek Robert A.
Bioplasty, Inc.
Cannon Alan W.
Paul N.
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