Tetrodotoxin-resistant sodium channel alpha subunit

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Using tissue cell culture to make a protein or polypeptide

Reexamination Certificate

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C435S006120, C435S069100, C435S252300, C530S350000, C536S023500, C536S024310

Reexamination Certificate

active

07972813

ABSTRACT:
The present invention is directed to a chimp sodium channel alpha subunit and methods and compositions for making and using the same.

REFERENCES:
patent: 4554101 (1985-11-01), Hopp
patent: 4861719 (1989-08-01), Miller
patent: 5093246 (1992-03-01), Cech et al.
patent: 5139941 (1992-08-01), Muzyczka et al.
patent: 5252479 (1993-10-01), Srivastava
patent: 5328688 (1994-07-01), Roizman
patent: 5380836 (1995-01-01), Rogart
patent: 5437982 (1995-08-01), Catterall et al.
patent: 5474935 (1995-12-01), Chatterjee et al.
patent: 5585362 (1996-12-01), Wilson et al.
patent: 5599673 (1997-02-01), Keating et al.
patent: 5622856 (1997-04-01), Natsoulis
patent: 5658776 (1997-08-01), Flotte et al.
patent: 5661033 (1997-08-01), Ho et al.
patent: 5670488 (1997-09-01), Gregory et al.
patent: 5686278 (1997-11-01), Williams et al.
patent: 5693509 (1997-12-01), Cotten et al.
patent: 5693756 (1997-12-01), Li et al.
patent: 5707618 (1998-01-01), Armentano et al.
patent: 5770414 (1998-06-01), Gage et al.
patent: 5773289 (1998-06-01), Samulski et al.
patent: 5776859 (1998-07-01), Nickel
patent: 5789390 (1998-08-01), Descamps et al.
patent: 5824544 (1998-10-01), Armentano et al.
patent: 5830725 (1998-11-01), Nolan et al.
patent: 5830727 (1998-11-01), Wang et al.
patent: 5834441 (1998-11-01), Philip et al.
patent: 5849571 (1998-12-01), Glorioso et al.
patent: 5851521 (1998-12-01), Branellec et al.
patent: 5856152 (1999-01-01), Wilson et al.
patent: 5863541 (1999-01-01), Samulski et al.
patent: 5879934 (1999-03-01), DeLuca
patent: 5888502 (1999-03-01), Guber et al.
patent: 5892018 (1999-04-01), Welsh et al.
patent: 6030810 (2000-02-01), Delgado et al.
patent: 6060271 (2000-05-01), Walewski et al.
patent: 6184349 (2001-02-01), Herman et al.
patent: 6335172 (2002-01-01), Delgado et al.
patent: 6479259 (2002-11-01), Herman et al.
patent: 6479498 (2002-11-01), Marquess et al.
patent: 6559154 (2003-05-01), Kang et al.
patent: 6607741 (2003-08-01), Boucher, Jr.
patent: 6613345 (2003-09-01), Boucher, Jr.
patent: 6646012 (2003-11-01), Choi et al.
patent: 6686193 (2004-02-01), Maher et al.
patent: 6756400 (2004-06-01), Chinn et al.
patent: WO 84/03564 (1984-09-01), None
patent: WO 91/09955 (1991-07-01), None
patent: WO 92/20808 (1992-11-01), None
patent: WO 93/23569 (1993-11-01), None
patent: WO 96/02651 (1996-02-01), None
patent: WO 03/016917 (2003-02-01), None
Baichwal et al., “Vectors for gene transfer derived from animal DNA viruses: Transient and stable expression of transferred genes,” Gene Transfer, Kucherlapati R, Ed., Plenum Press, New York,117-148 (1986).
Balazy, “Clinical management of chronic pain in spinal cord injury,”Clin J Pain, 8:102-110 (1992).
Barany and Merrifield, “Solid-phase peptide synthesis,” In: The Peptides, Gross and Meienhofer, Eds., Academic Press, New York, 1-284 (1979).
Bitter et al., “Expression and secretion vectors for yeast,”Methods in Enzymol, 153: 516-544 (1987).
Black et al, “Sodium channel mRNAs I, II and III in the CNS: cell-specific expression,” Mol Brain Res, 22:275-289 (1994).
Cane et al., “Harnessing the Biosynthetic Code: Combinations, Permutations, and Mutations,”Science, 282:63-68 (1998).
Coward et al., “Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states,”Pain, 85:41-50 (2000).
Devor, et al., “Na+ channel immunolocalization in peripheral mammalian axons and changes following nerve injury and neuroma formation,”J Neurosci, 13:1976-1992 (1993).
Dixon, “Efficient analysis of experimental observations,”Ann. Rev. Pharmacol. Toxicol., 20:441-462 (1980).
Drew et al., “Responses of spinal neurones to cutaneous and dorsal root stimuli in rats with mechanical allodynia after contusive spinal cord injury,”Brain Res, 893:59-69 (2001).
Elbashir et al., “Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells,”Nature, 411:494-498 (2001).
Fairbanks et al., “Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury,”Proc Natl Acad Sci, 97:10584-10589 (2000).
Fire et al.,“Potent and specific genetic interference by double-stranded RNA inCaenorhabditis elegans,”Nature, 391: 806-811 (1998).
Gallo et al., “Modulation of non-N-methyl-D-aspartate receptors in cultured cerebellar granule cells,”J. Neurochem, 54:1619-1625 (1990).
Hains et al., “Serotonergic neural precursor cell grafts attenuate bilateral hyperexcitability of dorsal horn neurons after spinal hemisection in rat,”Neuroscience, 116:1097-1110 (2001).
Hains et al., “Temporal plasticity of dorsal horn somatosensory neurons after acute and chronic spinal cord hemisection in rat,”Brain Res, 970:238-241 (2003).
Hannon, “RNA interference,”Nature, 418:244-251 (2002).
Hao et al., “Allodynia-like effects in rat after ischaemic spinal cord injury photochemically induced by laser irradiation,”Pain, 45:175-185 (1991).
Hefti, “Neurotrophic factor therapy for nervous system degenerative diseases”,J. Neurobiology, 25:1418-1435 (1994).
Houston et al., “The chemical-biological interface: developments in automated and miniaturised screening technology,”Curr. Opin. Biotechnol., 8: 734-740 (1997).
Hulsebosch et al., “Rodent model of chronic central pain after spinal cord contusion injury and effects of gabapentin,”J Neurotrauma, 17:1205-1217 (2000).
Ikeda-Yamasaki et al., “Projection map of the reaction center-light harvesting 1 complex fromRhodopseudomonas viridisat 10 Å resolution,”FEBS Lett., 425:505-508 (1998).
Jap et al., “2D crystallization: from art to science,”Ultramicros, 46:45-84 (1992).
Jayawickreme et al., “Gene expression systems in the development of high-throughput screens,”Curr. Opin. Biotechnol., 8: 629-634 (1997).
Johnson et al., “Peptide Turn Mimetics,” Chapter 14:366-378, Biotechnology and Pharmacy, Pezzuto JM et al., Eds., Chapman and Hall, New York (1993).
Kim et al., “An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat,”Pain, 50:355-363 (1992).
Kühlbrandt, “Two-dimensional crystallization of membrane proteins,” Q. Rev. Biophys., 25:1-49 (1992).
Kyte et al., “A simple method for displaying the hydropathic character of a protein,”J. Mol. Biol., 157:105-132 (1982).
Lacapère et al., “Two-dimensional crystallization of Ca-ATPase by detergent removal,”Biophys. J., 75:1319-1329 (1998).
Lai et al., “Inhibition of neuropathic pain by decreased expression of the tetrodotoxin-resistant sodium channel, NaV1.8,”Pain, 95:143-152 (2002).
Lindsey et al., “An analysis of changes in sensory thresholds to mild tactile and cold stimuli after experimental spinal cord injury in the rat,”Neurorehabil Neural Repair, 14:287-300 (2000).
Macejak et al., “Internal initiation of translation mediated by the 5′ leader of a cellular mRNA,”Nature, 353:90-94 (1991).
Mansikka et al., “Nerve injury-induced mechanical but not thermal hyperalgesia is attenuated in neurokinin-1 receptor knockout mice ,”Exp Neurol, 162:343-349 (2000).
Matzner et al., “Hyperexcitability at sites of nerve injury depends on voltage-sensitive Na+ channels,”J Neurophysiol, 72:349-359 (1994).
McManus et al., “Gene silencing in mammals by small interfering RNAs,”Nat. Rev. Genet., 3:737-747 (2002).
Merrifield, “Solid phase synthesis,”Science, 232:341-347 (1986).
Mills et al., “Strain and model differences in behavioral outcomes after spinal cord injury in rat ,”J. Neurotrauma, 18:743-756 (2001).
Montoya et al., “Two-dimensional crystallization and preliminary structure analysis of light harvesting II (B800-850) complex from the purple bacteriumRhodovulum sulfidophilum,” J. Mol. Biol., 250:1-10 (1995).
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