Tetrazolyl anthraquinones for inhibiting the release of spasmoge

Details Tetrazolyl anthraquinones for inhibiting the release of spasmoge Tetrazolyl anthraquinones for inhibiting the release of spasmoge

1972-11-29

1976-10-05

Drezin, Norman A.

Drug, bio-affecting and body treating compositions

Effervescent or pressurized fluid containing

Organic pressurized fluid

424269, A61K 3141

Patent

active

039845346

ABSTRACT:
Compounds of the general formula: ##SPC1##
Wherein X represents a 5-[1H]-tetrazolyl group, R.sub.1 represents a hydrogen atom, a halogen atom, a hydroxyl group or a group --OR.sub.2, (in which R.sub.2 may be a lower alkyl or alkenyl group containing from 1 to 6 carbon atoms optionally substituted by one or more hydroxy groups, an aryl group, an aryloxy group, an alkoxy group or a dialkylamino group) or a group --NR.sub.3 R.sub.4, in which R.sub.3 and R.sub.4 which may be the same or different, represent a hydrogen atom, a lower alkyl group containing from 1 to 6 carbon atoms, optionally substituted by a hydroxy group, or R.sub.3 and R.sub.4 together with the nitrogen atom may form a ring which may optionally be substituted with another heteroatom and pharmaceutically acceptable salts thereof.
These compounds have useful immunological activity and inhibit the release of spasmogen mediators.

REFERENCES:
patent: 3864493 (1975-02-01), Cairns et al.
patent: 3879544 (1975-04-01), Reisner et al.
patent: 3883653 (1975-05-01), Barth
patent: 3885038 (1975-05-01), Pfister et al.
Lobov et al., Chemical Abstracts, 66: 36740t (1967).
McManus et al., J. Org. Chem. 24 1464-1467 (1959).
Juby et al., J. Med. Chem. 11 pp. 111-117 (1968).

Affiliated with

Also associated with

Rating

Tetrazolyl anthraquinones for inhibiting the release of spasmoge does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Tetrazolyl anthraquinones for inhibiting the release of spasmoge, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Tetrazolyl anthraquinones for inhibiting the release of spasmoge will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-655662