Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1992-08-04
1993-11-16
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514382, 548253, C07D25704, C07D40704, C07D40904, A61K 3141
Patent
active
052624331
ABSTRACT:
A tetrazoleacetic acid derivative represented by the following general formula I: ##STR1## wherein in the formula I, R represents a hydrogen atom or a lower alkyl group; A is an alkylene group having 2 to 5 carbon atoms; Ar is selected from the group consisting of a phenyl group, a naphthyl group, a furyl group, a thienyl group, a benzofuryl group, and a benzothienyl group; wherein the Ar may be substituted with a lower alkyl group, a lower alkoxy group, a halogen atom, a lower haloalkyl group, an alkylthio group and an alkylsulfonylamino group shows excellent aldose reductase inhibitory activity, and is quite effective as an essential component of a preventive medicine and/or remedy for diabetic complications.
REFERENCES:
patent: 4937253 (1990-06-01), Gleason et al.
patent: 5068239 (1991-11-01), Inukai et al.
Agata Mitsuji
Goto Masayoshi
Horio Yoshihiro
Inukai Sinji
Ootake Yasuhiro
Springer David B.
Wakamoto Pharmaceutical Co., Ltd.
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