Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2008-12-17
2011-11-01
Hui, San-Ming (Department: 1628)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S688000, C548S250000
Reexamination Certificate
active
08048905
ABSTRACT:
Compounds of the formula I:or a pharmaceutically acceptable salt thereof, wherein, R1is optionally substituted tetrazolyl, R2is optionally substituted phenyl, optionally substituted pyridinyl or optionally substituted thienyl, and R3, R4, R5, R6R7and R8are as defined herein. Also provided are methods of using the compounds for treating diseases associated with the P2X3and/or a P2X2/3receptor antagonist and methods of making the compounds.
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Chen Li
Dillon Michael Patrick
Feng Lichun
Hawley Ronald Charles
Yang Minmin
Hall Robert C.
Hui San-Ming
Roche Palo Alto LLC
Zarek Paul
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