Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-

Details Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted- Tetrazole derivatives of [1-oxo-2-aryl or thienyl-2-substituted-

1978-03-23

1980-01-08

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260308D, 424269, 548253, A61K 31475, A61K 31235, C07D25704

Patent

active

041827643

ABSTRACT:
[1-Oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acid, derivatives thereof, their salts, esters and amides are disclosed. The products display a dual pharmaceutical utility in that they exhibit diuretic, saluretic and uricosuric activity. Also disclosed are processes for the preparation of such [1-oxo-2-aryl or thienyl-2-substituted-5-indanyloxy (or thio)]alkanoic acids, pharmaceutical compositions comprising therapeutically effective amounts of such compounds and methods of treatment comprising administering such compounds and compositions.

REFERENCES:
patent: 3668241 (1972-06-01), Cragoe et al.
patent: 3704314 (1972-01-01), Cragoe et al.
patent: 3984465 (1976-10-01), Cragoe et al.

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