Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Parasitic organism or component thereof or substance...
Patent
1980-07-11
1985-01-01
Rizzo, Nicholas S.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Parasitic organism or component thereof or substance...
424270, 548161, 548190, 548198, 548252, 548254, C07D25704
Patent
active
044915870
ABSTRACT:
6-(1H-Tetrazol-5-yl)thiazolo[3,2-a]pyrimidin-5-ones, 3-(1H-tetrazol-5-yl)-4H-pyrimido[2,1-b]benzothiazol-4-ones, and the corresponding imidazo- and triazolo- pyrimidines, thiones, and imines are useful as antiallergy and antiasthmatic compounds by virtue of their inhibitory action on the immediate hypersensitivity reaction in mammals and relaxant action on the tracheal muscle. Intermediates in the synthesis of these substances from 2-aminoazoles and ethoxymethylene malononitrile also have smooth muscle relaxant and immediate hypersensitivity reaction inhibitory activity.
REFERENCES:
patent: 3299087 (1967-01-01), Spivack et al.
patent: 3538086 (1970-11-01), Mair et al.
patent: 3689488 (1972-09-01), Dukes
patent: 3888983 (1975-06-01), Baetz
patent: 4014917 (1977-03-01), Carter
patent: 4033961 (1977-07-01), Schwender et al.
patent: 4041163 (1977-08-01), Biandra et al.
patent: 4072679 (1978-02-01), Denzel et al.
patent: 4083980 (1978-04-01), Schromm et al.
patent: 4122274 (1978-10-01), Juby
patent: 4223031 (1980-09-01), Covington et al.
Ogura et al., Chem. Pharm. Bull. 21(9), 2019-2025 (1973).
Antaki et al., J. Chem. Soc. 551-555 (1951).
Dunwell et al., J. Chem. Soc. (C), 2084-2087 (1971).
Gompper et al., Chem. Ber. 95, 2871-2880 (1962).
Galasko et al., J. South African Chem. Inst. 22(2), 121-127 (1969).
Richardson, Jr. et al., J. Med. Chem. 15, 1203-1206 (1972).
Alaimo, J. Heterocyclic Chem. 10, 769-772 (1973).
Covington Robert R.
Temple, Jr. Davis L.
Yevich Joseph P.
Mead Johnson & Company
Rizzo Nicholas S.
Ryan Richard P.
Uloth Robert H.
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