Tetrazole carboxylic acids and esters and inhibition of blood pl

Details Tetrazole carboxylic acids and esters and inhibition of blood pl Tetrazole carboxylic acids and esters and inhibition of blood pl

1990-02-13

1990-09-11

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548253, A61K 3141, C07D25704

Patent

active

049563769

ABSTRACT:
Heterocyclic acids and esters useful as inhibitors of mammalian blood platelet aggregation characterized by Formula I or II are disclosed. ##STR1## Formula I compounds are those wherein n is 6-9, R is hydrogen, lower alkyl or an alkali metal ion, and HET.sub.1 is the heterocyclic radical 5-(diphenylmethyl)-2H-tetrazol-2-yl.

REFERENCES:
patent: 3453285 (1969-07-01), Hayao
patent: 3962272 (1976-06-01), Katner
patent: 4059703 (1977-11-01), Burrell et al.
patent: 4652671 (1987-03-01), Bison et al.
patent: 4755518 (1988-07-01), Rafferty et al.

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