Tetrapeptides

Details Tetrapeptides Tetrapeptides

1976-03-01

1977-06-21

Phillips, Delbert R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2601125R, 424177, C07C10352

Patent

active

040310728

ABSTRACT:
New tetrapeptides having the formula A-Pro-Pro-Tyr(benzyl)-Ser(benzyl)-R.sub.1 wherein A is t-butoxycarbonyl, cyclohexylcarbonyl, benzyloxycarbonyl and p-nitrobenzyloxycarbonyl; Pro is D-Pro or L-Pro; Tyr(benzyl) is D-Tyr(benzyl) or L-Tyr(benzyl); Ser(benzyl) is D-Ser(benzyl) or L-Ser(benzyl) and R.sub.1 is lower alkoxy, hydrazino, amino, lower alkylamino or di(lower alkyl)amino.

REFERENCES:
patent: 3725380 (1973-04-01), Konig et al.
J. M. Stewart and J. D. Young, "Solid Phase Peptide Synthesis", Freeman and Co., San Francisco, 1969, pp. 9-13.
J. D. Roberts and M. C. Caserio, "Basic Principles of Organic Chemistry", Benjamin, Inc., N.Y., 1965, pp. 531, 563-564.
E. Schroder and K. Lubke, "The Peptides", vol. 1, Academic Press, N.Y., 1965, pp. 79-80.

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