Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,... – Reduced antigenicity – reduced ability to bind complement – or...
Patent
1978-09-13
1980-04-22
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Immunoglobulin, antiserum, antibody, or antibody fragment,...
Reduced antigenicity, reduced ability to bind complement, or...
2601125R, A61K 3700, C07C10352
Patent
active
041995686
ABSTRACT:
Tetrapeptide amides of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, A and B represent certain specified substituent groups and where n is 2-5, p is 1-5 and r is 1 or 2. The compounds exhibit pharmacological activity when tested in the transmurally stimulating guinea pig ileum preparation indicating their affinity for opiate receptor sites and they may therefore be used in man for those conditions where an opiate-like effect is indicated.
REFERENCES:
Nature 268, 1977, pp. 547-549.
Handa Balraj K.
Morgan Barry A.
Rance Michael J.
Grove, Jr. Jesse B.
Phillips Delbert R.
Reckitt & Colman Products Limited
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