Tetrapeptide

Details Tetrapeptide Tetrapeptide

1985-06-17

1988-12-20

Tarcza, John E.

Chemistry: molecular biology and microbiology

Spore forming or isolating process

435180, 530811, 530330, 530324, 530812, 530815, C12N 0500, C12N 1108, C07K 710, C07K 1702

Patent

active

047925256

ABSTRACT:
The peptide X-Arg-Gly-Asp-R-Y wherein X is H or at least one amino acid and Y is OH or at least one amino acid, and R is an amino acid selected from Thr or Cys, or other amino acid, having the same cell-attachent activity as fibronectin and the peptide X-Arg-Gly-Asp-Ser-Y, wherein X and Y, having said activity are disclosed.

REFERENCES:
patent: 3883393 (1975-05-01), Knazek et al.
patent: 4511653 (1985-04-01), Play et al.
patent: 4578079 (1986-03-01), Ruoslahti et al.
Grinnell et al., Cell 19, pp. 517-525 (1980).
Bernard et al., Biochemistry 22, pp. 5213-5223 (1983).
Kohno et al., Journal of Biological Chemistry 259 (22), pp. 13668-13673 (1984).
Seyer et al., Biochemistry 20, pp. 2621-2627 (1981).
Hynes, R. O., 1987, "Fibronectins: A Family of Complex and Versatile ADhesive Glycoproteins Derived from a Single Gene". The Harvey Lectures, Series 81, at p. 134.
Lam et al., 1987, "Evidence that Argionyl-Glycyl-Aspartate Peptides and Fibrinogen & Chain Peptides Share a Common Binding Site on Platelets". Journal of Biological Chemistry 262: 947 at p. 947.
Babel et al., European Journal of Biochemistry, 143, pp. 545-556 (1984).

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