Tetrapeptide

Details Tetrapeptide Tetrapeptide

1985-06-17

1986-09-30

Apley, Richard J.

Prosthesis (i.e., artificial body members), parts thereof, or ai

Implantable prosthesis

623 66, 623 1, 604175, 514 2, 514802, 435178, 435177, 435180, 525 541, 525329, 530300, A61F 200, A61K 3700, C07K 100, C07K 104

Patent

active

046145176

ABSTRACT:
The peptide X-Arg-Gly-Asp-Ser-Y wherein X is H or at least one amino acid and Y is OH or at least one amino acid having the same cell-attachment activity as fibronectin.

REFERENCES:
Seitz et al.; "Effect of Fibronectin . . . ", J. of Biomed. Mat. Res.; vol. 16, #3; pp. 195-207; 5/1982.
Hynes, et al., Cell Surface Fibronectin and Oncogenic Transformation, J. Supramolecular Structure, 11:95-104 (1979).
Hahn, Lian-Hsien E. and Kenneth M. Yamada, Isolation and Biological Characterization of Active Fragments of the Adhesive Glycoprotein Fibronectin, Cell, 18:1043-1051, 1979.
Sekiguchi, Kiyotoshi and Sen-Itiroh Hakomori, Functional Domain Structure of Fibronectin, Proc. Natl. Acad. Sci., 77:2661-2665, 1980.
Grinnell, Frederick, et al., Distribution of Fibronectin During Wound Healing in Vivo, J. Invest. Dermatol., 76:181-189, 1981.
McDonagh, R. P., et al., Amino Acid Sequence of the Factor XIII.sub.a Acceptor Site in Bovine Plasma Fibronectin, Febs Letters, 127:174-178, 1981.
Ruoslahti, Erkki, et al., Alignment of Biologically Active Domains in the Fibronectin Molecule, J. Biol. Chem., 256:7277-7281, 1981.
Pande, Hema, et al., Comparative Structural Studies of Human Plasma and Amniotic Fluid Fibronectins, Bioch. Biophy. Res. Comm., 101:265-272, 1981.
Pande, Hema and John E. Shively, NH.sub.2 -Terminal Sequences of DNA-, Heparin-, and Gelatin-Binding Tryptic Fragments from Human Plasma Fibronectin, Arch. Bioch. Biophy., 213:258-265, 1982.
Pierschbacher, Michael D., et al., The Cell Attachment Domain of Fibronectin, J. Biol. Chem., 257:9593-9597, 1982.
Vibe-Pedersen, Karen, et al., Amino Acid Sequence of a Peptide from Bovine Plasma Fibronectin Containing a Free Sulfhydryl Group (Cysteine), Febs. Letters, 142:26-30, 1982.
Sekiguchi, Kiyotoshi, et al., Monoclonal Antibodies Directed to Two Different Domains of Human Plasma Fibronectin: Their Specificities, Fed. Eur. Bich. Soc., 142:243-246, 1982.
Ehrismann, Ruth, et al., Arrangement of Attachment-Promoting, Self-Association, and Heparin-Binding Sites in Horse Serum Fibronectin, J. Biol. Chem., 257:7381-7387, 1982.
Clark, Richard A. F., et al., Fibronectin is Produced by Blood Vessels in Response to Injury, J. Exp. Med., 156:646-651, 1982.
Hynes, Richard O. and Kenneth M. Yamada, Fibronectins: Multifunctional Modular Glycoproteins, J. Cell. Biol., 95:369-377, 1982.
Petersen, Torbene, et al., Partial Primary Structure of Bovine Plasma Fibronectin: Three Types of Internal Homology, Proc. Natl. Acad. Sci., 80:137-141, 1983.
Grinnell, Frederick, Cell Attachment and Spreading Factors in Growth and Maturation Factors (Dr. Gordon Guroff, Ed.) John Wiley & Sons, Inc., 1983.
Grinnell, Frederick, The Role of Fibronectin in the Bioreactivity of Material Surfaces in Biocompatible Polymers, Metals, and Composites, (Ed. Michael Szycher), Technomic Publishing, Lancaster, Pennsylvania, 1983.
Hayashi, Masao and Kenneth M. Yamada, Domain Structure of the Carboxyl-Terminal Half of Human Plasma Fibronectin, J. Biol. Chem., 258:3332-3340, 1983.
Kornblihtt, Alberto R., et al., Isolation and Characterization of cDNA Clones for Human and Bovine Fibronectins, Proc. Natl. Acad. Sci., 80:3218-3222, 1983.
Pierschbacher, Michael, et al., Synthetic Peptide with Cell Attachment Activity of Fibronectin, Proc. Natl. Acad. Sci., 80:1224-1227, 1983.

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