Tetraline derivatives, their production and pharmaceutical compo

Details Tetraline derivatives, their production and pharmaceutical compo Tetraline derivatives, their production and pharmaceutical compo

1981-03-12

1983-10-18

Brust, Joseph Paul

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Virus or component thereof

260349, 2604045, 260465D, 260465E, 560 27, 560 43, 560 59, 560 61, 560133, 560250, 560255, 564 56, 564 86, 564167, 564428, 424300, 424304, 424309, 424311, 424312, 424321, 424322, 424324, 424330, A61K 31655, A61K 31275, C07C12160, C07C11700

Patent

active

044105193

ABSTRACT:
An optically active or racemic 2-amino-5-hydroxy-1,2,3,4-tetrahydronaphthalene wherein the nitrogen atom of the amino group carrier two alkyl groups, one of which is unsubstituted and the other is substituted by at least one functional group, or a physiologically hydrolysable ester thereof in free base form or in the form of an acid addition salt thereof is provided which is active against heart circulatory disorders and Morbus Parkinson and inhibits prolactin secretion inhibition.

REFERENCES:
patent: 3296249 (1967-01-01), Bell
patent: 3991207 (1976-11-01), Sarges et al.
patent: 4010202 (1977-03-01), Sugihara et al.
patent: 4035512 (1977-07-01), Sugihara et al.
patent: 4057582 (1977-11-01), Dunnigan et al.
McDermed, et al., Journal of Medicinal Chemistry, (1975), vol. 18, pp. 362-367.
McDermed, et al., Journal of Medicinal Chemistry, (1976), vol. 19, pp. 547-549.
Hacksell, et al., Journal of Medicinal Chemistry, (1979), vol. 22, pp. 1469-1475.

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