Tetrahydroquinoxaline dopamine D4 receptor antagonists

Details Tetrahydroquinoxaline dopamine D4 receptor antagonists Tetrahydroquinoxaline dopamine D4 receptor antagonists

1998-03-05

1999-03-23

Ambrose, Michael G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

544353, A61K 31495, C07D24138

Patent

active

058859942

ABSTRACT:
This invention relates to compounds that are antagonists of dopamine D4 receptors having Formula I below ##STR1## This invention also relates to methods of treating psychosis and schizophrenia using a compound that is an antagonist of dopamine D4 receptors, and to pharmaceutically acceptable compositions that contain a dopamine D4 receptor antagonist.

REFERENCES:
patent: 3133069 (1964-05-01), Ash et al.
patent: 4091101 (1978-05-01), Lumma, Jr. et al.

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